Synthesis a Novel Complexes of VO(II),Mn(II),Fe(II) ,Co(II), Ni(II), Cu(II)and Pt(IV) Derived from Schiff’s Base of Pyridoxal and 2-amino-4-nitrophenol and Study their Biological Activates

This work describes the synthesis of novel ligand (H2L2) (4-((2-hydroxy-5-nitrophenyl)imino)methyl)-5(hydroxymethyl)-2methylpyridin-3-ol) type (NOO) donor atoms. When it coordinates with metal ions[V2+, Fe2+,Co2+ and Pt4+] general formula K2[M(L2)2].XH2O K2[VO(L2)(OSO3)].H2O . can form tridentate structures. The was synthesized from reaction pyridoxal hydrochloride 2-amino-4-nitrophenol in ethanol (as a solvent) at mole ratio 1:1 thoroughly mixed refluxed for 6-8 hrs monitored using TLC (Ethylactate/hexane 1:1). structures complexes were characterised spectroscopic techniques such as (FT-IR, 1HNMR, 13CNMR, UV-Vis, Mass spectroscopy). In addition, molar conductance, magnetic susceptibility, elemental analysis, thermo gravimetric, melting points also measured complexes. antibacterial activities obtained products tested against G- bacteria (Klebsiella pneumoniae pseudomonas), G+ (Staphylococcus aureus Bacillus subtilis). antifungal action (Candida albicans). results good both tests.